Description

Hertraz Injection (Trastuzumab)

Generic name: Trastuzumab
Brand name: Hertraz
Drug class: Monoclonal antibody (anti-HER2 targeted therapy)
Available strengths: 150 mg and 440 mg injections.

Uses

Hertraz is used to treat:

• HER2-positive breast cancer
• HER2-positive metastatic breast cancer
• HER2-positive gastric (stomach) cancer and gastroesophageal junction cancer.

How It Works

Trastuzumab targets the HER2 (Human Epidermal Growth Factor Receptor 2) protein found in excess on some cancer cells. By binding to HER2 receptors, it slows or stops cancer cell growth and helps the immune system destroy cancer cells.

Administration

• Given intravenously (IV infusion) by a qualified healthcare professional.
• The dose and treatment schedule depend on the type of cancer, body weight, and treatment plan.
• It should not be self-administered.

Common Side Effects

• Fever and chills
• Fatigue
• Nausea
• Headache
• Diarrhea
• Cough
• Rash
• Insomnia
• Infections
• Low blood cell counts (anemia, decreased white blood cells, platelets).

Serious Side Effects

Patients should seek medical attention if they experience:

• Shortness of breath
• Swelling of legs or arms
• Persistent cough
• Signs of heart problems (heart failure or reduced heart function)
• Severe allergic or infusion-related reactions.

Precautions

• Heart function is usually monitored before and during treatment.
• Inform your doctor if you have heart disease.
• Avoid pregnancy during treatment and follow your oncologist’s advice regarding contraception.
• Breastfeeding is generally not recommended during treatment.

Storage

• Store refrigerated at 2°C–8°C.
• Do not freeze